Is a
Patent attributes
Patent Applicant
Current Assignee
Patent Jurisdiction
Patent Number
Patent Inventor Names
Cagan Gurer0
Naxin Tu0
Andrew J. Murphy0
Lynn Macdonald0
Date of Patent
December 26, 2017
0Patent Application Number
141853010
Date Filed
February 20, 2014
0Patent Citations Received
Patent Primary Examiner
Patent abstract
The invention provides genetically modified non-human animals that express chimeric human/non-human T cell co-receptor polypeptides (e.g., CD4, CD8α, CD8β), as well as embryos, cells, and tissues comprising the same. Also provided are constructs for making said genetically modified animals and methods of making the same.
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