Is a
Patent attributes
Patent Jurisdiction
Patent Number
Date of Patent
December 26, 2017
Patent Application Number
14696140
Date Filed
April 24, 2015
Patent Citations Received
...
Patent Primary Examiner
Patent abstract
The present invention provides, among other things, methods of purifying messenger RNA (mRNA) including the steps of (a) precipitating mRNA from an impure preparation; (b) subjecting the impure preparation comprising precipitated mRNA to a purification process involving membrane filtration such that the precipitated mRNA is captured by a membrane; and (c) eluting the captured precipitated mRNA from the membrane by re-solubilizing the mRNA, thereby resulting in a purified mRNA solution. In some embodiments, a purification process involving membrane filtration suitable for the present invention is tangential flow filtration.
Timeline
No Timeline data yet.
Further Resources
No Further Resources data yet.
