A downhole probe is adapted to be supported in drill string sections having different internal diameters with the use of a set of interchangeable centralizers. Each centralizer is dimensioned to snugly receive the downhole probe and to bear against the bore wall of a drill-string section. Interchangeable axial supports such as spiders may also be provided in a set. The downhole probe may comprise a slick body. As drilling progresses the downhole probe may be adapted to be received in drill string sections of varying diameters.