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US Patent 9861713 PSMA-binding agents and uses thereof

Patent 9861713 was granted and assigned to Johns Hopkins University on January, 2018 by the United States Patent and Trademark Office.

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Is a

Patent attributes

Patent Applicant

Johns Hopkins University

Current Assignee

Johns Hopkins University

Patent Jurisdiction

United States Patent and Trademark Office

Patent Number

Patent Inventor Names

Martin G. Pomper0

Ronnie Charles Mease0

Ying Chen0

Date of Patent

January 9, 2018

Patent Application Number

14987032

Date Filed

January 4, 2016

Patent Citations Received

US Patent 11851407 Synthesis of the radiolabeled prostate-specific membrane antigen (PSMA) inhibitor [

0

US Patent 12070513 PSMA-binding agents and uses thereof

0

US Patent 11998620 PSMA targeted compounds and uses thereof

0

US Patent 11708393 Targeted non-invasive imaging probes of EGFR expressing cells

0

Patent Primary Examiner

Michael G. Hartley

Patent abstract

Prostate-specific membrane antigen (PSMA) binding compounds having radioisotope substituents are described, as well as chemical precursors thereof. Compounds include pyridine containing compounds, compounds having phenylhydrazine structures, and acylated lysine compounds. The compounds allow ready incorporation of radionuclides for single photon emission computed tomography (SPECT) and positron emission tomography (PET) for imaging, for example, prostate cancer cells and angiogenesis.

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