Is a
Patent attributes
Patent Jurisdiction
Patent Number
Patent Inventor Names
Josephus Johannes De Kimpe0
Derick Gert Wansink0
Gerard Johannes Platenburg0
Date of Patent
February 13, 2018
Patent Application Number
14809483
Date Filed
July 27, 2015
Patent Citations Received
...
Patent Primary Examiner
Patent abstract
The current invention provides for methods and medicaments that apply oligonucleotide molecules complementary only to a repetitive sequence in a human gene transcript, for the manufacture of a medicament for the diagnosis, treatment or prevention of a cis-element repeat instability associated genetic disorders in humans. The invention hence provides a method of treatment for cis-element repeat instability associated genetic disorders. The invention also pertains to modified oligonucleotides which can be applied in method of the invention to prevent the accumulation and/or translation of repeat expanded transcripts in cells.
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