A method and apparatus for three-dimensional or multi-view video encoding and decoding using VSP (view synthesis prediction) with uniform sub-block partition are disclosed. For a current texture block comprising multiple partition blocks, the system derives a single partition decision and partitions each partition block of the current texture block into multiples sub-blocks according to the single partition decision. The VSP processing is then applied to each sub-block to derive the inter-view prediction using VSP. The single partition decision is derived using depth samples of the depth block in a reference view.