Is a
Patent attributes
Patent Jurisdiction
Patent Number
Patent Inventor Names
Luc Berghman0
Walter Bottje0
Billy Hargis0
Sherryll Layton0
Date of Patent
March 13, 2018
0Patent Application Number
146231050
Date Filed
February 16, 2015
0Patent Citations Received
Patent Primary Examiner
Patent abstract
Provided herein are vaccine vectors including an antigenic polypeptide and an HMGB1 polypeptide present on the surface of the vaccine vector. Compositions comprising the vaccine vectors are also provided and include a pharmaceutically acceptable carrier, suitably a carrier for oral or nasal administration. Also provided are methods of enhancing immune responses, in particular antibody immune response and suitably an IgA response, by administering the vaccine vectors or compositions disclosed herein to a subject.
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