US Patent RE39792 Method for culturing Chinese hamster ovary cells

Patent RE39792 was granted and assigned to Smithkline Beecham Limited on August, 2007 by the United States Patent and Trademark Office.

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Michael J. Keen0

Nicholas T. Rapson0

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Patent abstract

A biochemically defined culture medium for culturing engineered Chinese hamster ovary (CHO) cell lines, which is essentially free from protein, lipid and carbohydrate isolated from an animal source, having water, an osmolality regulator, a buffer, an energy source, amino acids including L-glutamine, an inorganic or recombinant iron source, and a synthetic or recombinant growth factor, and optionally non-ferrous metal ions vitamins and cofactors. Also cells adapted to grow in such a culture medium.

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