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US Patent RE49542 Method for the detection of cancer

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Is a

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Patent attributes

Patent Applicant

Guardant Health

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Patent Jurisdiction

United States Patent and Trademark Office

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Patent Number

Date of Patent

June 6, 2023

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Patent Application Number

140391680

Date Filed

September 27, 2013

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Patent Citations

US Patent 7824889 Digital amplification

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US Patent 7935487 Method of detecting tumor-associated DNA in plasma or serum from humans without cancer

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US Patent 7937225 Systems, methods and software arrangements for detection of genome copy number variation

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US Patent 9404156 Varietal counting of nucleic acids for obtaining genomic copy number information

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US Patent RE44596 Method for the detection of cancer

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US Patent 7208275 Detection of extracellular tumor-associated nucleic acid in blood plasma or serum using nucleic acid amplification assays

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US Patent 7282335 Detection of extracellular tumor-associated nucleic acid in blood plasma or serum using nucleic acid amplification assays

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US Patent 7410764 Detection of extracellular tumor-associated nucleic acid in blood plasma or serum using nucleic acid amplification assays

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Patent Primary Examiner

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CPC Code

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The present invention relates to a method for the diagnosis and/or the follow up of the evolution of cancer, which includes the analysis and quantification of over expressed and amplified genes in the plasma/serum of cancer patients or persons suspected to harbor cancer. This is achieved by analyzing together the amount of DNA and RNA of certain genes in the plasma/serum of cancer patients that are the reflection of a gene amplification and/or a gene over expression in comparison to healthy controls.

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