Is a
Patent attributes
Patent Jurisdiction
Patent Number
Date of Patent
July 17, 2018
Patent Application Number
15583384
Date Filed
May 1, 2017
Patent Citations Received
Patent Primary Examiner
Patent abstract
We provide new monoclonal antibody inhibitors of coagulases for treatment of S. aureus. The monoclonal antibodies are useful in targeting the SC N-terminus and inhibiting SC-ProT activation. The monoclonal antibodies are able to bind to and interfere with, modulate, and/or inhibit the binding interactions between the staphylocoagulase protein and its ligand protein prothrombin in blood and tissues. The antibodies are effective in inhibiting the activation of prothrombin.
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