Is a
Patent attributes
Patent Jurisdiction
Patent Number
Date of Patent
April 30, 2019
Patent Application Number
16027538
Date Filed
July 5, 2018
Patent Citations
Patent Citations Received
Patent Primary Examiner
Patent abstract
We provide new monoclonal antibody inhibitors of coagulases for treatment of S. aureus. The monoclonal antibodies are useful in targeting the SC N-terminus and inhibiting SC-ProT activation. The monoclonal antibodies are able to bind to and interfere with, modulate, and/or inhibit the binding interactions between the staphylocoagulase protein and its ligand protein prothrombin in blood and tissues. The antibodies are effective in inhibiting the activation of prothrombin.
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