Is a
Patent attributes
Patent Jurisdiction
Patent Number
Patent Inventor Names
William R Church0
Date of Patent
February 2, 2021
0Patent Application Number
163992710
Date Filed
April 30, 2019
0Patent Citations
Patent Primary Examiner
Patent abstract
We provide new monoclonal antibody inhibitors of coagulases for treatment of S. aureus. The monoclonal antibodies are useful in targeting the SC N-terminus and inhibiting SC-ProT activation. The monoclonal antibodies are able to bind to and interfere with, modulate, and/or inhibit the binding interactions between the staphylocoagulase protein and its ligand protein prothrombin in blood and tissues. The antibodies are effective in inhibiting the activation of prothrombin.
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