Patent 10030244 was granted and assigned to Alnylam Pharmaceuticals on July, 2018 by the United States Patent and Trademark Office.
The invention relates to RNAi agents, e.g., double-stranded RNAi agents, targeting the Serpina1 gene, and methods of using such RNAi agents to inhibit expression of Serpina1 and methods of treating subjects having a Serpina1 associated disease, such as a liver disorder.