Is a
Patent attributes
Patent Jurisdiction
Patent Number
Date of Patent
November 13, 2018
Patent Application Number
15118245
Date Filed
February 16, 2015
Patent Citations Received
Patent Primary Examiner
Patent abstract
Provided are methods of generating chimeric antigen receptors (CAR). In some embodiments, library screening of CAR is performed by generating a vector encoding the CAR from random attachment of vectors from libraries of vectors encoding antigen-binding domains (e.g., scFv regions), hinge regions, and endodomains. In some embodiments, the vectors contain a transposon.
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