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US Patent 10144953 Modification of DNA on magnetic beads

Patent 10144953 was granted and assigned to Exact Sciences (company) on December, 2018 by the United States Patent and Trademark Office.

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Patent attributes

Patent Applicant

Exact Sciences (company)

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Current Assignee

Exact Sciences (company)

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Patent Jurisdiction

United States Patent and Trademark Office

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Patent Number

Patent Inventor Names

Tobias Charles Zutz0

Brian Aizenstein0

Graham P. Lidgard0

Hatim Allawi0

Michael J. Domanico0

Oliver Hunt0

Date of Patent

December 4, 2018

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Patent Application Number

150681210

Date Filed

March 11, 2016

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Patent Citations Received

US Patent 12024750 Methylation markers and targeted methylation probe panel

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US Patent 10704083 Modification of DNA on magnetic beads

US Patent 11685958 Methylation markers and targeted methylation probe panel

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US Patent 11410750 Methylation markers and targeted methylation probe panel

Patent Primary Examiner

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Patent abstract

Provided herein is technology related to the chemical modification and purification of DNA. Specifically, the technology provides methods for performing a bisulfite conversion reaction on small amounts of single-stranded, fragmented DNA and performing the subsequent desulfonation and purification steps on magnetic beads.

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