Is a
Patent attributes
Patent Jurisdiction
Patent Number
Patent Inventor Names
Stephen Hoge0
Iain McFadyen0
Joshua Frederick0
Kerry Benenato0
Susannah Hewitt0
Vladimir Presnyak0
Ailin Bai0
Ellalahewage Sathyajith Kumarasinghe0
Date of Patent
January 8, 2019
0Patent Application Number
159958890
Date Filed
June 1, 2018
0Patent Citations Received
0
...
Patent Primary Examiner
Patent abstract
The disclosure relates to compositions and methods for the preparation, manufacture and therapeutic use of combinations of immunomodulatory polynucleotides (e.g., mRNAs) encoding an immune response primer polypeptide (e.g., an interleukin 23 (IL-23) polypeptide or an interleukin 36γ (IL-36-gamma) polypeptide), and an immune response co-stimulatory signal polypeptide (e.g., an OX40L polypeptide).
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