Is a
Patent attributes
Patent Jurisdiction
Patent Number
Patent Inventor Names
Susannah Hewitt0
Vladimir Presnyak0
Ailin Bai0
Ellalahewage Sathyajith Kumarasinghe0
Iain McFadyen0
Joshua Frederick0
Kerry Benenato0
Stephen G. Hoge0
Date of Patent
July 27, 2021
0Patent Application Number
170716850
Date Filed
October 15, 2020
0Patent Citations
Patent Citations Received
Patent Primary Examiner
Patent abstract
The disclosure relates to compositions and methods for the preparation, manufacture and therapeutic use of combinations of immunomodulatory polynucleotides (e.g., mRNAs) encoding an immune response primer polypeptide (e.g., an interleukin 23 (IL-23) polypeptide or an interleukin 36γ (IL-36-gamma) polypeptide), and an immune response co-stimulatory signal polypeptide (e.g., an OX40L polypeptide).
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