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US Patent 10188652 Compositions and methods for treating insomnia

Patent 10188652 was granted and assigned to Eisai on January, 2019 by the United States Patent and Trademark Office.

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Patent Applicant

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Current Assignee

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Patent Jurisdiction

United States Patent and Trademark Office

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Patent Number

Patent Inventor Names

Yasuhiro Zaima0

Nobuo Yoshida0

Nobuya Suzuki0

Yurie Akimoto0

Gina Pastino0

Margaret Moline0

Date of Patent

January 29, 2019

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Patent Application Number

155196760

Date Filed

October 21, 2015

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Patent Citations Received

US Patent 11872206 Purified forms of rofecoxib, methods of manufacture and use

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US Patent 11559509 Purified forms of rofecoxib, methods of manufacture and use

US Patent 11576890 Purified forms of rofecoxib, methods of manufacture and use

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US Patent 11026944 Compositions and methods for treating insomnia

US Patent 11617735 Purified forms of rofecoxib, methods of manufacture and use

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Patent Primary Examiner

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Patent abstract

In the present invention, compound such as (1R,2S)-2-(((2,4-dimethylpyrimidin-5-yl)oxy)methyl)-2-(3-fluorophenyl)-N-(5-fluoropyridin-2-yl) cyclopropanecarboxamide have been found to be potent orexin receptor antagonists, and may be useful in the treatment of sleep disorders such as insomnia, as well as for other therapeutic uses.

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