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US Patent 11617735 Purified forms of rofecoxib, methods of manufacture and use

Patent 11617735 was granted and assigned to Tremeau Pharmaceuticals, Inc. on April, 2023 by the United States Patent and Trademark Office.

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The subject matter disclosed herein relates to rofecoxib, also known as TRM-201 or RXB-201, its method of manufacture, and use. In certain aspects, the highly pure or substantially pure rofecoxib as provided herein has a favorable purity profile and is the active ingredient in a pharmaceutical composition that is administered to treat or prevent a number of conditions, including pain associated with a condition caused by a bleeding disorder.

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