Is a
Patent attributes
Patent Applicant
0
Current Assignee
0
Patent Jurisdiction
Patent Number
Patent Inventor Names
Marianne Brüggemann0
Xiangang Zou0
Date of Patent
February 5, 2019
0Patent Application Number
152305640
Date Filed
August 8, 2016
0Patent Citations Received
Patent Primary Examiner
Patent abstract
The present invention provides in a first aspect a mouse in which the λ (lambda) light chain locus has been functionally silenced. In one embodiment, the mouse λ light chain locus was functional silenced by deletion of gene segments coding for the λ light chain locus. In a further aspect, a mouse containing functionally silenced λ and κ (kappa) L chain loci was produced. The invention is useful for the production of antibodies, for example heterologous antibodies, including heavy chain only antibodies.
Timeline
No Timeline data yet.
Further Resources
No Further Resources data yet.
