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US Patent 10273207 Covalent inhibitors of kras G12C

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Patent Citations Received
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US Patent 12134620 Heterocyclic spiro compounds and methods of use thereof for the treatment of cancer
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US Patent 11878985 Substituted quinazolines as inhibitors of KRAS G12C
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Patent abstract

Irreversible inhibitors of G12C mutant K-Ras protein are provided. Also disclosed are methods to modulate the activity of G12C mutant K-Ras protein and methods of treatment of disorders mediated by G12C mutant K-Ras protein.

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Official Website
https://pdfpiw.uspto.gov/.piw?Docid=1027320700
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US Patent 11639346 Quinazoline derivatives as modulators of mutant KRAS, HRAS or NRAS
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Infobox
Is a
Patent
Patent
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Patent Jurisdiction
United States Patent and Trademark Office
United States Patent and Trademark Office
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Patent Number
102732070
Date of Patent
April 30, 2019
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Patent Application Number
158913040
Date Filed
February 7, 2018
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Official Website
https://pdfpiw.uspto.gov/.piw?Docid=102732070
Patent Citations Received
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US Patent 10646488 Conjugates of cereblon binding compounds and G12C mutant KRAS, HRAS or NRAS protein modulating compounds and methods of use thereof
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US Patent 10689356 Inhibitors of KRAS G12C mutant proteins
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US Patent 10723738 Inhibitors of KRAS G12C mutant proteins
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US Patent 10730867 Inhibitors of KRAS G12C mutant proteins
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US Patent 10829458 Substituted quinazoline compounds and methods of use thereof
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US Patent 10858343 Inhibitors of KRAS G12C mutant proteins
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US Patent 10875842 Inhibitors of KRAS G12C mutant proteins
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US Patent 10882847 Inhibitors of KRAS G12C mutant proteins
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US Patent 10919850 Covalent inhibitors of KRas G12C
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US Patent 10927125 Substituted cinnolines as inhibitors of KRAS G12C
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US Patent 10975071 Inhibitors of KRAS G12C mutant proteins
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US Patent 11021470 2-substituted quinazoline compounds comprising a substituted heterocyclic group and methods of use thereof
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US Patent 11059819 Fused hetero-hetero bicyclic compounds and methods of use thereof
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US Patent 11274093 Fused bicyclic benzoheteroaromatic compounds and methods of use thereof
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US Patent 11279689 1-(3-(6-(3-hydroxynaphthalen-1-yl)benzofuran-2-yl)azetidin-1 yl)prop-2-en-1-one derivatives and similar compounds as KRAS G12C modulators for treating cancer
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US Patent 11358959 Benzothiophene and benzothiazole compounds and methods of use thereof
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US Patent 11377441 Covalent inhibitors of KRAS
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Patent Primary Examiner
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Golam M. Shameem
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Patent Citations Received
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US Patent 11377441 Covalent inhibitors of KRAS
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Infobox
Patent Citations Received
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US Patent 11377441 Covalent inhibitors of KRAS
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