Is a
Patent attributes
Patent Jurisdiction
Patent Number
Patent Inventor Names
Guangping Gao0
James M. Wilson0
Luk Vandenberghe0
Date of Patent
May 28, 2019
0Patent Application Number
146246710
Date Filed
February 18, 2015
0Patent Citations Received
...
Patent Primary Examiner
Patent abstract
A method of correcting singletons in a selected AAV sequence in order to increasing the packaging yield, transduction efficiency, and/or gene transfer efficiency of the selected AAV is provided. This method involves altering one or more singletons in the parental AAV capsid to conform the singleton to the amino acid in the corresponding position(s) of the aligned functional AAV capsid sequences.
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