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US Patent 10336786 Pharmaceutical targeting of a mammalian cyclic di-nucleotide signaling pathway

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Patent attributes

Patent Jurisdiction

United States Patent and Trademark Office

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Patent Number

Patent Inventor Names

Zhijian Chen0

Heping Shi0

Jiaxi Wu0

Lijun Sun0

Chuo Chen0

Date of Patent

July 2, 2019

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Patent Application Number

146535860

Date Filed

December 16, 2013

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Patent Citations Received

US Patent 10696710 Pharmaceutical targeting of a mammalian cyclic di-nucleotide signaling pathway

US Patent 11492368 Pharmaceutical targeting of a mammalian cyclic di-nucleotide signaling pathway

US Patent 10633411 Pharmaceutical targeting of a mammalian cyclic di-nucleotide signaling pathway

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Patent abstract

Cyclic-GMP-AMP synthase (cGAS) and cyclic-GMP-AMP (cGAMP), including 2′3-cGAMP, 2′2-cGAMP, 3′2′-cGAMP and 3′3′-GAMP, are used in pharmaceutical formulations (including vaccine adjuvants), drug screens, therapies and diagnostics.

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