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US Patent 11492368 Pharmaceutical targeting of a mammalian cyclic di-nucleotide signaling pathway

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Patent Jurisdiction

United States Patent and Trademark Office

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Patent Number

Patent Inventor Names

Zhijian Chen0

Chuo Chen0

Heping Shi0

Jiaxi Wu0

Lijun Sun0

Date of Patent

November 8, 2022

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Patent Application Number

169031730

Date Filed

June 16, 2020

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Patent Citations

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Cyclic-GMP-AMP synthase (cGAS) and cyclic-GMP-AMP (cGAMP), including 2′3-cGAMP, 2′2-cGAMP, 3′2′-cGAMP and 3′3′-GAMP, are used in pharmaceutical formulations (including vaccine adjuvants), drug screens, therapies, and diagnostics.

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