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US Patent 10508129 Pharmaceutical targeting of a mammalian cyclic di-nucleotide signaling pathway

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Is a

Patent attributes

Patent Jurisdiction

United States Patent and Trademark Office

Patent Number

Patent Inventor Names

Zhijian Chen0

Heping Shi0

Jiaxi Wu0

Lijun Sun0

Chuo Chen0

Date of Patent

December 17, 2019

Patent Application Number

16405660

Date Filed

May 7, 2019

Patent Citations Received

US Patent 10696710 Pharmaceutical targeting of a mammalian cyclic di-nucleotide signaling pathway

US Patent 11492368 Pharmaceutical targeting of a mammalian cyclic di-nucleotide signaling pathway

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US Patent 10633411 Pharmaceutical targeting of a mammalian cyclic di-nucleotide signaling pathway

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Patent Primary Examiner

Patent abstract

Cyclic-GMP-AMP synthase (cGAS) and cyclic-GMP-AMP (cGAMP), including 2′3-cGAMP, 2′2-cGAMP, 3′2′-cGAMP and 3′3′-GAMP, are used in pharmaceutical formulations (including vaccine adjuvants), drug screens, therapies, and diagnostics.

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