A heat dissipation structure of an electronic device includes a casing, an upper motherboard located within the casing, a lower motherboard located within the casing and space apart from the upper motherboard, and a heat dissipation device located between the upper motherboard and the lower motherboard. The heat dissipation device extends out from between the upper motherboard and the lower motherboard to contact the casing. Between the upper motherboard and the lower motherboard is located a plurality of heat generating components directly in contact with the heat dissipation device, so that heat generated by the heat generating components is dissipated to the casing.