Is a
Patent attributes
Patent Jurisdiction
Patent Number
Patent Inventor Names
Meena0
Naoki Iwamoto0
Sethumadhavan Divakaramenon0
Subramanian Marappan0
Chandra Vargeese0
Christopher J. Francis0
David Charles Donnell Butler0
Genliang Lu0
...
Date of Patent
October 22, 2019
0Patent Application Number
161390910
Date Filed
September 23, 2018
0Patent Citations
Patent Citations Received
...
Patent Primary Examiner
Patent abstract
Among other things, the present disclosure relates to designed oligonucleotides, compositions, and methods thereof. In some embodiments, provided oligonucleotide compositions provide altered splicing of a transcript. In some embodiments, provided oligonucleotide compositions have low toxicity. In some embodiments, provided oligonucleotide compositions provide improved protein binding profiles. In some embodiments, provided oligonucleotide compositions have improved delivery. In some embodiments, provided oligonucleotide compositions have improved uptake. In some embodiments, the present disclosure provides methods for treatment of diseases using provided oligonucleotide compositions.
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