Is a
Patent attributes
Patent Jurisdiction
Patent Number
Date of Patent
November 5, 2019
Patent Application Number
15300024
Date Filed
March 27, 2015
Patent Citations Received
...
Patent Primary Examiner
Patent abstract
This disclosure describes, generally, a modified form of CD 16, genetically-modified cells that express the modified CD 16, and methods that involve the genetically-modified cells. The modified form of CD 16 can exhibit increased anti-tumor and/or anti- viral activity due, at least in part, to reduced susceptibility to ADAM17-mediated shedding upon NK cell stimulation.
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