Is a
Patent attributes
Patent Jurisdiction
Patent Number
Date of Patent
June 28, 2022
Patent Application Number
17233979
Date Filed
April 19, 2021
Patent Primary Examiner
This disclosure describes, generally, a modified form of CD16, genetically-modified cells that express the modified CD16, and methods that involve the genetically-modified cells. The modified form of CD16 can exhibit increased anti-tumor and/or anti-viral activity due, at least in part, to reduced susceptibility to ADAM17-mediated shedding upon NK cell stimulation.
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