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US Patent 10501555 Humanized anti-trop-2 monoclonal antibodies and uses thereof

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Is a

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Patent attributes

Patent Jurisdiction

United States Patent and Trademark Office

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Patent Number

Patent Inventor Names

Emanuela Guerra0

Saverio Alberti0

Date of Patent

December 10, 2019

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Patent Application Number

155325980

Date Filed

December 4, 2015

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Patent Citations Received

US Patent 11957693 Combination MCL-1 inhibitors with anti-cancer agents

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US Patent 11931424 Combination MCL-1 inhibitors with anti-body drug conjugates

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Patent Primary Examiner

Laura B Goddard

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Patent abstract

The present invention refers to humanized anti-Trop-2 antibodies and their fragments, derivatives and conjugates that are able to recognise and bind with high affinity distinct regions of the Trop-2 molecule. The present invention also teaches the use of such antibodies and of pharmaceutical compositions thereof for diagnosis and therapy of human pathologies, in particular cancer.

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