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US Patent 10537615 IL-15-based molecules and methods of use thereof

Patent 10537615 was granted and assigned to Altor BioScience on January, 2020 by the United States Patent and Trademark Office.

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Is a

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Patent attributes

Patent Applicant

Altor BioScience

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Current Assignee

Altor BioScience

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Patent Jurisdiction

United States Patent and Trademark Office

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Patent Number

Patent Inventor Names

Wenxin Xu0

Bai Liu0

Hing C. Wong0

Peter Rhode0

Date of Patent

January 21, 2020

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Patent Application Number

159215120

Date Filed

March 14, 2018

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Patent Citations Received

US Patent 12104178 DHFR tunable protein regulation

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US Patent 11498950 Fusion molecules and IL-15 variants

US Patent 11318201 Multimeric IL-15-based molecules

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US Patent 11365231 Interleukin 15 (IL-15) variants

US Patent 11369679 Multimeric IL-15-based molecules

US Patent 11890323 Method of treating cancer with composition comprising IL-15-based molecules and BCG

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US Patent 11925676 Method for treating neoplasia with an anti-CD38 antibody and an IL-15:IL-15R complex

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US Patent 11992516 Compositions comprising IL-15-based molecules and immune checkpoint inhibitor antibodies

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Patent Primary Examiner

Bridget E Bunner

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Patent abstract

The invention features combination therapies using an IL-15-based superagonist complex and an antibody to effectively treat subjects with cancer and infectious diseases.

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