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US Patent 10543208 Treatment of gliomas using organonitro compound combination therapy

Patent 10543208 was granted and assigned to EpicentRx on January, 2020 by the United States Patent and Trademark Office.

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Patent attributes

Current Assignee

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Patent Jurisdiction

United States Patent and Trademark Office

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Patent Number

Patent Inventor Names

Jan Scicinski0

Bryan T. Oronsky0

Date of Patent

January 28, 2020

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Patent Application Number

159898620

Date Filed

May 25, 2018

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Patent Citations

US Patent 10149832 Cyclic nitro compounds, pharmaceutical compositions thereof and uses thereof

US Patent 10342778 Treatment of brain metastases using organonitro compound combination therapy

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Patent Citations Received

US Patent 11925617 Cyclic nitro compounds, pharmaceutical compositions thereof and uses thereof

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US Patent 11008287 Sulfoxyalkyl organonitro and related compounds and pharmaceutical compounds for use in medicine

US Patent 11660286 Methods and compositions comprising a nitrite-reductase promoter for treatment of medical disorders and preservation of blood products

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US Patent 11701351 Treatment of gliomas using organonitro compound combination therapy

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US Patent 11744859 Compositions and methods for parenteral administration of therapeutic agents

US Patent 11510901 Methods and compositions utilizing RRx-001 combination therapy for radioprotection

US Patent 11576895 Compositions and methods for intravenous administration of 2-bromo-1-(3,3-dinitroazetidin-1-yl)ethanone

Patent Primary Examiner

Kristin A Vajda

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Patent abstract

The invention provides therapeutic methods and kits for treating a glioma using a particular dosing regimen of the organonitro compound ABDNAZ, radiation therapy, and one of temozolomide, irinotecan, or bevacizumab.

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