Is a
Patent attributes
Patent Jurisdiction
Patent Number
Patent Inventor Names
Eric Tran0
Steven A. Rosenberg0
Yong-Chen Lu0
Date of Patent
February 11, 2020
0Patent Application Number
157589540
Date Filed
September 9, 2016
0Patent Citations Received
Patent Primary Examiner
Patent abstract
Disclosed is an isolated or purified T cell receptor (TCR) having antigenic specificity for mutated Kirsten rat sarcoma viral oncogene homolog (KRAS) presented in the context of an HLA-Cw*0802 molecule. Related polypeptides and proteins, as well as related nucleic acids, recombinant expression vectors, host cells, populations of cells, and pharmaceutical compositions are also provided. Also disclosed are methods of detecting the presence of cancer in a mammal and methods of treating or preventing cancer in a mammal.
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