Is a
Patent attributes
Patent Jurisdiction
Patent Number
Patent Inventor Names
Zhiyuan Cao0
Lei Xiao0
Zhao Wu0
Chengfei Pu0
Date of Patent
February 18, 2020
Patent Application Number
16146218
Date Filed
September 28, 2018
Patent Citations Received
Patent Primary Examiner
Patent abstract
The present disclosure relates to compositions and methods for enhancing T cell response and/or CAR cell expansion in vivo and/or in vitro. For example, a cell may comprise a first chimeric antigen receptor (CAR) and a second CAR, wherein a binding domain of the first CAR binds a first antigen, and a binding domain of the second CAR binds a second antigen. The first antigen is different from the second antigen. In embodiments, the first CAR may recognize a surface molecule of a blood cell.
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