Is a
Patent attributes
Patent Jurisdiction
Patent Number
Patent Inventor Names
Zhiyuan Cao0
Chengfei Pu0
Zhao Wu0
Lei Xiao0
Date of Patent
September 3, 2024
0Patent Application Number
171735040
Date Filed
February 11, 2021
0Patent Citations
Patent Primary Examiner
CPC Code
Patent abstract
The present disclosure relates to compositions and methods for treating cancer. For example, a modified cell may include a polynucleotide comprising an NFAT promoter, a nucleotide sequence encoding therapeutic agent, and a nucleotide sequence encoding a VHL-interaction domain of HIF1α, wherein the therapeutic agent comprises, for example, IL-12, IL-6, and/or IFNγ.
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