US Patent 12076343 Engineered safety in cell therapy
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US Patent 12076343 Engineered safety in cell therapy
Article
Patent abstract
The present disclosure relates to compositions and methods for treating cancer. For example, a modified cell may include a polynucleotide comprising an NFAT promoter, a nucleotide sequence encoding therapeutic agent, and a nucleotide sequence encoding a VHL-interaction domain of HIF1α, wherein the therapeutic agent comprises, for example, IL-12, IL-6, and/or IFNγ.
Infobox
Is a
Patent Jurisdiction
Patent Number
Patent Inventor Names
Chengfei Pu0
Lei Xiao0
Zhao Wu0
Zhiyuan Cao0
Date of Patent
September 3, 2024
0Patent Application Number
171735040
Date Filed
February 11, 2021
0Patent Citations
Patent Primary Examiner
CPC Code
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