Is a
Patent attributes
Patent Jurisdiction
Patent Number
Date of Patent
February 21, 2017
Patent Application Number
15093643
Date Filed
April 7, 2016
Patent Citations Received
Patent Primary Examiner
Patent abstract
The present disclosure relates to compositions and methods for reducing immune tolerance associated with CAR T cell therapy. Embodiments of the present disclosure include isolated nucleic acid sequence comprising a nucleic acid sequence that encodes modified programmed cell death protein 1 (PD-1) and a nucleic acid sequence that encodes chimeric antigen receptor (CAR).
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