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US Patent 10588966 Methods and compositions for inhibiting Akt3

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Patent attributes

Patent Jurisdiction

United States Patent and Trademark Office

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Patent Number

Patent Inventor Names

Samir N. Khleif0

Mikayel Mkrtichyan0

Date of Patent

March 17, 2020

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Patent Application Number

162691460

Date Filed

February 6, 2019

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Patent Citations

US Patent 10342868 Methods and compositions for inhibiting Akt3

US Patent 10292978 Specific Akt3 inhibitor and uses thereof

US Patent 10159731 Methods and compositions for inhibiting Akt3

Patent Citations Received

US Patent 11957673 Specific AKT3 activator and uses thereof

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US Patent 10980878 Methods and compositions for modulating Akt3 activity

US Patent 11013735 Specific Akt3 inhibitor and uses thereof

US Patent 11291719 Methods and compositions for modulating Akt3

Patent Primary Examiner

D Margaret M Seaman

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Patent abstract

Compounds and compositions for selectively inhibiting Akt3 are provided. Methods of using the compounds are also provided. Because Akt3 modulates the suppressive function of natural Tregs and the polarization of induced Tregs, the disclosed compounds are useful for modulating immune responses.

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