Is a
Patent attributes
Patent Jurisdiction
Patent Number
Patent Inventor Names
Mikayel Mkrtichyan0
Samir N. Khleif0
Date of Patent
May 25, 2021
0Patent Application Number
165905660
Date Filed
October 2, 2019
0Patent Citations
Patent Citations Received
Patent Primary Examiner
Patent abstract
Methods of selectively inhibiting Akt3 are provided. It has been discovered that 4-[(6-nitroquinolin-4-yl)amino]-N-[4-(pyridin-4-ylamino)phenyl]benzamide selectively inhibits Akt3. Because Akt3 modulates the suppressive function of natural Tregs and the polarization of induced Tregs, 4-[(6-nitroquinolin-4-yl)amino]-N-[4-(pyridin-4-ylamino)phenyl]benzamide can be used for modulating immune responses.
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