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US Patent 11013735 Specific Akt3 inhibitor and uses thereof

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Patent Citations Received
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US Patent 11957673 Specific AKT3 activator and uses thereof
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Patent abstract

Methods of selectively inhibiting Akt3 are provided. It has been discovered that 4-[(6-nitroquinolin-4-yl)amino]-N-[4-(pyridin-4-ylamino)phenyl]benzamide selectively inhibits Akt3. Because Akt3 modulates the suppressive function of natural Tregs and the polarization of induced Tregs, 4-[(6-nitroquinolin-4-yl)amino]-N-[4-(pyridin-4-ylamino)phenyl]benzamide can be used for modulating immune responses.

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Patent Inventor Names
Mikayel Mkrtichyan0
Samir N. Khleif0
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Official Website
https://pdfpiw.uspto.gov/.piw?Docid=110137350
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https://pdfpiw.uspto.gov/.piw?Docid=11013735
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 US Patent 11013735 Specific Akt3 inhibitor and uses thereof

Infobox
Is a
Patent
Patent
Patent jurisdiction
United States Patent and Trademark Office
United States Patent and Trademark Office
Patent number
11013735
Date of patent
May 25, 2021
Patent application number
16590566
Date Filed
October 2, 2019
Patent citations
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US Patent 10159731 Methods and compositions for inhibiting Akt3
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US Patent 10292978 Specific Akt3 inhibitor and uses thereof
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US Patent 10342868 Methods and compositions for inhibiting Akt3
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US Patent 10525049 Specific Akt3 inhibitor and uses thereof
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US Patent 10588966 Methods and compositions for inhibiting Akt3
Patent primary examiner
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Nizal S Chandrakumar

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