Is a
Patent attributes
Patent Jurisdiction
Patent Number
Date of Patent
March 2, 2021
Patent Application Number
16825996
Date Filed
March 20, 2020
Patent Citations
Patent Citations Received
Patent Primary Examiner
Patent abstract
Provided herein are chimeric antigen receptors (CARs), such as those specific for BCMA, that have improved properties, including increased CAR T cell binding to BCMA and improved CAR T cell killing of BCMA-expressing cancer cells. Use of the CARs in immune cells (e.g., T cells), compositions (e.g., CARs and nucleic acid constructs encoding the same), and methods are also contemplated.
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