Patent 10947317 was granted and assigned to Mersana Therapeutics on March, 2021 by the United States Patent and Trademark Office.
This disclosure provides NaPi2b-targeted antibody-drug conjugates (e.g., NaPi2b-targeted antibody-polymer-drug conjugates) that specifically bind to the extracellular region of SLC34A2, and to methods of using such conjugates in a variety of therapeutic, diagnostic, and prophylactic indications.