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US Patent 10961287 Extended recombinant polypeptides and compositions comprising same

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Patent attributes

Patent Applicant

Amunix Pharmaceuticals, Inc.

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Patent Jurisdiction

United States Patent and Trademark Office

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Patent Number

Patent Inventor Names

Wayne To0

Benjamin Spink0

Chia-wei Wang0

Jeffrey L. Cleland0

Joshua Silverman0

Nathan Geething0

Volker Schellenberger0

Willem P. Stemmer0

Date of Patent

March 30, 2021

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Patent Application Number

158873130

Date Filed

February 2, 2018

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Patent Citations

US Patent 10172953 XTEN conjugate compositions and methods of making same

US Patent 10000543 Glucose-regulating polypeptides and methods of making and using same

US Patent 10035839 Blood glucose lowering compound

US Patent 10421798 Factor VIII compositions and methods of making and using same

Patent Citations Received

US Patent 11981744 Chimeric polypeptide assembly and methods of making and using the same

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US Patent 12071456 Extended recombinant polypeptides and compositions comprising same

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US Patent 11713358 Chimeric polypeptide assembly and methods of making and using the same

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Patent Primary Examiner

Randall L Beane

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Patent abstract

The present invention relates to compositions comprising biologically active proteins linked to extended recombinant polypeptide (XTEN), isolated nucleic acids encoding the compositions and vectors and host cells containing the same, and methods of using such compositions in treatment of glucose-related diseases, metabolic diseases, coagulation disorders, and growth hormone-related disorders and conditions.

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