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US Patent 10975369 Methods for purification of messenger RNA

Patent 10975369 was granted and assigned to Translate Bio on April, 2021 by the United States Patent and Trademark Office.

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Patent abstract

The present invention relates, in part, to methods for large-scale purification of mRNA. The method includes, at least, a step of centrifuging an mRNA suspension in a centrifuge comprising a porous substrate at a speed sufficient to remove process contaminants and to precipitate purified mRNA composition onto the porous substrate.

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