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US Patent 10975374 Combination vectors and methods for treating cancer

Patent 10975374 was granted and assigned to American Gene Technologies on April, 2021 by the United States Patent and Trademark Office.

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Patent abstract

A composition for treating cancer is disclosed. The composition includes a lentiviral particle and an aminobisphosphonate drug. The lentiviral particle is capable of infecting a target cell, such as a cancer cell, and includes an envelope protein optimized for targeting such target cell and a viral vector. The viral vector includes a small RNA optimized to target an FDPS mRNA sequence. The aminobisphosphonate drug includes zoledronic acid.

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Patent Inventor Names
Charles David Pauza0
Haishan Li0
Lingzhi Xiao0
Mei-Ling Liou0
Tyler Lahusen0
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Official Website
https://pdfpiw.uspto.gov/.piw?Docid=109753740
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Infobox
Is a
Patent
Patent
0
Patent Applicant
American Gene Technologies
American Gene Technologies
0
Current Assignee
American Gene Technologies
American Gene Technologies
0
Patent Jurisdiction
United States Patent and Trademark Office
United States Patent and Trademark Office
0
Patent Number
109753740
Date of Patent
April 13, 2021
0
Patent Application Number
169438000
Date Filed
July 30, 2020
0
Official Website
https://pdfpiw.uspto.gov/.piw?Docid=109753740
Patent Citations
‌
US Patent 10023880 Methods and compositions for the activation of gamma-delta T-cells
0
‌
US Patent 10036038 HIV pre-immunization and immunotherapy
0
‌
US Patent 10036040 Methods and compositions for the activation of gamma-delta T-cells
0
‌
US Patent 10137144 Methods and compositions for the activation of gamma-delta T-cells
0
‌
US Patent 10208295 MRNA therapy for phenylketonuria
0
‌
US Patent 10233464 HIV pre-immunization and immunotherapy
0
‌
US Patent 10420789 Methods and compositions for the activation of gamma-delta T-cells
0
‌
US Patent 10472649 Methods and compositions for the activation of gamma-delta T-cells
0
Patent Primary Examiner
‌
Sean McGarry
0
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Website URL
https://pdfpiw.uspto.gov/.piw?Docid=10975374
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 US Patent 10975374 Combination vectors and methods for treating cancer

Infobox
Is a
Patent
Patent
Patent applicant
American Gene Technologies
American Gene Technologies
Current assignee
American Gene Technologies
American Gene Technologies
Patent jurisdiction
United States Patent and Trademark Office
United States Patent and Trademark Office
Patent number
10975374
Date of patent
April 13, 2021
Patent application number
16943800
Date Filed
July 30, 2020
Patent citations
‌
US Patent 10023880 Methods and compositions for the activation of gamma-delta T-cells
‌
US Patent 10036038 HIV pre-immunization and immunotherapy
‌
US Patent 10036040 Methods and compositions for the activation of gamma-delta T-cells
‌
US Patent 10137144 Methods and compositions for the activation of gamma-delta T-cells
‌
US Patent 10208295 MRNA therapy for phenylketonuria
‌
US Patent 10233464 HIV pre-immunization and immunotherapy
‌
US Patent 10420789 Methods and compositions for the activation of gamma-delta T-cells
‌
US Patent 10472649 Methods and compositions for the activation of gamma-delta T-cells
Patent primary examiner
‌
Sean McGarry

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