US Patent 11008400 Anti-5T4 antibodies and antibody-drug conjugates
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Patent abstract
The present disclosure relates to CDR defined antibodies targeting the 5T4 oncofoetal antigen (TPBG, 5T4, Wnt Activated Inhibitory Factor 1, WAIF1) which exhibit a binding affinity for human 5T4 antigen which is in the same order of magnitude as their affinity for cynomolgus monkey 5T4. Antibody-drug conjugates (ADCs), and their use in the treatment of human solid tumours and haematological malignancies are claimed.
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Patent Inventor Names
Gerardus Joseph Andreas Ariaans0
Jan Schouten0
Marion Blomenrohr0
Miranda Maria Cornelia Van der Lee0
Patrick Gerhard Groothuis0
Rudy Gerardus Elisabeth Coumans0
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Patent Citations Received
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Patent Jurisdiction
Patent Number
110084000
Date of Patent
May 18, 2021
0Patent Application Number
157787590
Date Filed
November 24, 2016
0Official Website
Patent Primary Examiner
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US Patent 11008400 Anti-5T4 antibodies and antibody-drug conjugates
Infobox
Is a
Patent jurisdiction
Patent number
11008400
Date of patent
May 18, 2021
Patent application number
15778759
Date Filed
November 24, 2016
Patent primary examiner
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