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US Patent 11021737 Compositions and methods for analyte detection

Patent 11021737 was granted and assigned to President and Fellows of Harvard College on June, 2021 by the United States Patent and Trademark Office.

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Patent attributes

Patent Applicant

President and Fellows of Harvard College

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Current Assignee

President and Fellows of Harvard College

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Patent Jurisdiction

United States Patent and Trademark Office

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Patent Number

Patent Inventor Names

Michael Super0

Daniel Levner0

George M. Church0

Je-hyuk Lee0

Date of Patent

June 1, 2021

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Patent Application Number

169415850

Date Filed

July 29, 2020

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Patent Citations

US Patent 10138509 Method for generating a three-dimensional nucleic acid containing matrix

US Patent 10494662 Method for generating a three-dimensional nucleic acid containing matrix

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US Patent 10545075 Methods and compositions for preparing biological specimens for microscopic analysis

US Patent 10267808 Molecular indicia of cellular constituents and resolving the same by super-resolution technologies in single cells

US Patent 10266888 Method and apparatus for volumetric imaging of a three-dimensional nucleic acid containing matrix

US Patent 10494667 Spatially encoded biological assays

US Patent 10227639 Compositions and methods for analyte detection

Patent Citations Received

US Patent 12116625 Barcode diffusion-based spatial omics

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US Patent 11549136 Compositions and methods for analyte detection

US Patent 11549139 Chemical compositions and methods of using same

US Patent 11542554 Method and apparatus for volumetric imaging

US Patent 11566276 Compositions and methods for analyte detection

US Patent 11566277 Compositions and methods for analyte detection

US Patent 11788123 Systems and methods for high-throughput image-based screening

US Patent 11447807 Methods of combining the detection of biomolecules into a single assay using fluorescent in situ sequencing

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Patent Primary Examiner

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Patent abstract

Methods of making a three-dimensional matrix of nucleic acids within a cell is provided.

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