Is a
Patent attributes
Patent Applicant
Current Assignee
Patent Jurisdiction
Patent Number
Patent Inventor Names
Leslie S. Johnson0
Ezio Bonvini0
Ling Huang0
Nadine Tuaillon0
Date of Patent
June 8, 2021
Patent Application Number
16156382
Date Filed
October 10, 2018
Patent Citations Received
Patent Primary Examiner
Patent abstract
This invention relates to antibodies that specifically bind HER2/neu, and particularly chimeric 4D5 antibodies to HER2/neu, which have reduced glycosylation as compared to known 4D5 antibodies. The invention also relates to methods of using the 4D5 antibodies and compositions comprising them in the diagnosis, prognosis and therapy of diseases such as cancer, autoimmune diseases, inflammatory disorders, and infectious disease.
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