A surgical instrument assembly configured to be operably attached to and detached from a surgical robot interface is disclosed. The surgical instrument assembly comprises a shaft assembly comprising an end effector and a closure drive member configured to move a second jaw relative to a first jaw of the end effector. The surgical instrument assembly further comprises a control assembly, wherein the shaft assembly is operably coupled with the control assembly, and wherein the control assembly comprises a housing, a closure drive system configured to actuate the closure drive member, and an exterior closure drive actuator exterior to the housing and configured to be actuated by a clinician to manually rotate a rotary input drive of the closure drive system to move the second jaw relative to the first jaw when the surgical instrument assembly is not operably attached to the surgical robot interface.