US Patent 11072664 Interferon receptor 1 antibodies and their uses
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Patent abstract
The present invention provides isolated human monoclonal antibodies that bind to IFNAR-1 and that are capable of inhibiting the biological activity of Type I interferons. Immunoconjugates, bispecific molecules and pharmaceutical compositions comprising the antibodies of the invention are also provided. The invention also provides methods for inhibiting Type I interferon-mediated disorders using the antibodies of the invention, including methods for treating autoimmune disorders, transplant rejection or Graft Versus Host Disease using the antibodies of the invention.
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Patent Inventor Names
Alison Witte0
Josephine M. Cardarelli0
Mohan Srinivasan0
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Patent Number
110726640
Date of Patent
July 27, 2021
0Patent Application Number
165031960
Date Filed
July 3, 2019
0Official Website
Patent Citations
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US Patent 11072664 Interferon receptor 1 antibodies and their uses
Infobox
Is a
Patent jurisdiction
Patent number
11072664
Date of patent
July 27, 2021
Patent application number
16503196
Date Filed
July 3, 2019
Patent primary examiner
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